Immunophenotypic differences between neoplastic and non-neoplastic androgen-producing cells containing and lacking Reinke crystals
نویسندگان
چکیده
منابع مشابه
mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells.
Increased mast cell burden is observed in the inflamed tissues and affected organs and tissues of patients with mast cell proliferative disorders. However, normal mast cells participate in host defense, so approaches to preferentially target clonally expanding mast cells are needed. We found that mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) are up-regulated in neoplastic and ...
متن کاملNeoplastic and non-neoplastic ovarian disease in Zimbabwean women.
Disease of the ovary are a significant cause of morbidity and mortality amongst Zimbabwean women. There is however, scanty data regarding the types and extent of these conditions. A retrospective review of histologically diagnosed ovarian disease was carried out in order to determine the types, prevalence and age distribution of ovarian pathology seen in Harare over a 22 month period. Pathologi...
متن کاملNon-Neoplastic and Neoplastic Pleural Endpoints Following Fiber Exposure
Exposure to asbestos fibers is associated with non-neoplastic pleural diseases including plaques, fibrosis, and benign effusions, as well as with diffuse malignant pleural mesothelioma. Translocation and retention of fibers are fundamental processes in understanding the interactions between the dose and dimensions of fibers retained at this anatomic site and the subsequent pathological reaction...
متن کاملLysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.
Autotaxin (ATX) is a tumor cell motility-stimulating factor originally isolated from melanoma cell supernatant that has been implicated in regulation of invasive and metastatic properties of cancer cells. Recently, we showed that ATX is identical to lysophospholipase D, which converts lysophosphatidylcholine to a potent bioactive phospholipid mediator, lysophosphatidic acid (LPA), raising the p...
متن کاملNature and dynamics of nucleosome release from neoplastic and non-neoplastic cells.
BACKGROUND Circulating nucleosomes are elevated in the blood of patients with malignant and non-malignant diseases. Here, we investigated the nature and the dynamics of their release in functional cell studies. MATERIALS AND METHODS Leukemia blasts were exposed to the intrinsic inducers of apoptotic cell death, cytosine arabinoside (AraC; 10 μg/ml) and etoposide (50 μg/ml), and cell death mar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Virchows Archiv
سال: 2016
ISSN: 0945-6317,1432-2307
DOI: 10.1007/s00428-016-2028-4